Developed by Boaz and co-workers at the Eastman Chemical Company as a three step synthesis from PPFA. Applications that result in >80% ee are primarily in Rh catalysed hydrogenation, with one example of Ir catalysis. Literature covered until end 2017 (7 entries).
The synthesis of the optimised (and not commercially available) ligand for this reaction is available here.
Absolute configuration not stated, but for the phenyl-substituted product tentatively assigned as R.
Absolute configuration of ligand and mol% loading of ligand and Rh complex not stated. Neither is the E/Z ratio of the substrate, the reaction temperature and time, and the intrinsic diastereoselectivity of the substrate (i.e. dr using an achiral catalyst).
Ir – Hydrogenation TA08-19-938